Marcus Mariota threw three touchdown passes as the Washington Commanders claimed a 33-31 victory over Seattle to end the Seahawks' long winning streak.
Seattle had won a dozen games in a row, following up last season’s Super Bowl triumph by starting their campaign with back-to-back triumphs, but Mariota starred in the absence of the injured Jayden Daniels.
Also crucial in the Commanders’ first win of the season was Kain Medrano intercepting Sam Darnold’s pass and sprinting 50 yards for a touchdown as Seattle tasted defeat for the first time since November.
Chris Boswell kicked the go-ahead field goal as the Pittsburgh Steelers bounced back from their defeat to the New England Patriots by edging out the Cincinnati Bengals 30-27.
The Bengals’ hopes of avoiding a first defeat of the season ended when Joe Burrow fumbled in the final minute after being strip-sacked by Derrick Harmon.
Trevor Lawrence threw touchdown passes for Josh Cameron, Jakobi Meyers and Parker Washington to lift the Jacksonville Jaguars to an impressive 35-6 win over the Patriots.
Injuries continue to mount up for the New York Giants, who lost quarterback Jaxson Dart last week and Brian Burns went off with a knee problem in a 12-7 victory over the Tennessee Titans.
Spencer Shrader’s 53-yard field goal, his fourth of the game, helped the Indianapolis Colts defeat the Houston Texans 19-17.
Deshaun Watson and Harold Fannin Jr combined for two touchdown passes as the Cleveland Browns overcame the Carolina Panthers 21-18.
Josh Allen’s two rushing touchdowns led the Buffalo Bills to a 24-16 win over the Los Angeles Chargers, the Kansas City Chiefs defeated the Miami Dolphins 24-10 and the Detroit Lions beat the New York Jets 31-24.
Brock Purdy threw for four touchdown passes as the San Francisco 49ers remained unbeaten with a 36-30 win over the Arizona Cardinals, while the Minnesota Vikings are also 3-0 after they saw off the winless Tampa Bay Buccaneers 23-16.
The Buccaneers also lost quarterback Baker Mayfield with a dislocated thumb in the fourth quarter.
Tyler Loop kicked a last-ditch field goal from 56 yards to give the Baltimore Ravens a 34-31 win over the Dallas Cowboys, who had drawn level with seven seconds remaining, while the Las Vegas Raiders came from 11 points down to beat the New Orleans Saints 35-27.
Bo Nix crossed for a touchdown from close range in the final minute as the Denver Broncos came from 16-0 down at half-time to beat the Los Angeles Rams 30-26.
